Full Title BIOPROCESS ENGINEERING PRACTICAL

Short Title BIOPROCESS ENGR PRACT

Code BIO07029
Level 07
Credit 05

Author Tobin, Kieran
Department Applied Sciences

Subject Area Bio Tech/Eng/Chem
Attendence N/A%
Fee

Description
This Biopharma laboratory practical module will provide students with practical knowledge, know-how and skills associated with the monitoring and control of modern biopharmaceutcial manufacturing systems. The relevant learning is achieved through the completion of a sequence of laboratory-based and pilot-plant based practicals and experiments using dedicated control sysem test rigs that are designed to impart the required expertise. There will also be some research project work associated with the laboratory practicals.

Indicative Syllabus
The range of lab-based and pilot-plant based control system practicals may include some or all of the following items: GMP gowning/garbing for cleanroom entry; overview of main control systems for upstream and downstream bioprocesses; the control instrumentation including actuators and sensors for different control loops; the calibration of control instrumentation; the operation and configuration of a HMI (human machine interface) system for control loops; the architecture, operation and programming of a typical PLC system; write a PLC programme using several inputs and outputs for a number of different software functions (timers, counters etc.); develop and test SCADA screens to read/write information for a PLC system.












Learning Outcomes
On completion of this module the learner will/should be able to
  1. Demonstrate a range of practical know-how and skills associated with relevant practical lab. control and monitoring systems.

  2. Conduct a range of control system experiments based around a dedicated control rig for a modern bioprocessing system.

  3. Follow a sequence of control system instructions for the design and operation of bioprocessing control systems.

  4. Perform some defined research work related to the practical lab. control system work ; interpret and critically evaluate the data and results obtained from this research work in a report document.

  5. Take responsibility for and direct the work of other individuals in a quasi-GMP environment.

  6. Demonstrate effective communication skills both orally and in written format.


Assessment Strategies
A variety of assessment strategies will be employed for this module including the following: quizzes, assignments, lab. reports.

Module Dependencies
Pre Requisite Modules
BIO07027
Co Requisite Modules
None
Incompatible Modules
None

Coursework Assessment Breakdown %
Course Work / Continuous Assessment 100 %

Coursework Assessment Breakdown

Description Outcome Assessed % of Total Assessment Week
Practical Evaluation Observation assessment of practical skills. 1,2 20 Week 1
Other Exam Day 1 of Lab. Practicals. 1,2,3,4 10 Week 1
Other Exam Day 2 of Lab. Practicals. 1,2,3,4 10 Week 1
Written Report Research-based Lab. Report. 4,5,6 60 End of Term


End Exam Assessment Breakdown

Description Outcome Assessed % of Total Assessment Week


Distance Learning Mode Workload

Type Location Description Hours Frequency Avg Weekly Workload

Total Average Weekly Learner Workload 0.00 Hours

Part Time Mode Workload

Type Location Description Hours Frequency Avg Weekly Workload
Lecture Not Specified Preparatory study material. 4 Once Per Semester 0.27
Laboratory Practical Science Laboratory Attendance at laboratory practicals. 16 Once Per Semester 1.07
Independent Learning UNKNOWN Lab. Practical Report Document. 3 Weekly 3.00

Total Average Weekly Learner Workload 1.34 Hours

Full Time Mode Workload

Type Location Description Hours Frequency Avg Weekly Workload

Total Average Weekly Learner Workload 0.00 Hours

Online Learning Mode Workload

Type Location Description Hours Frequency Avg Weekly Workload

Total Average Weekly Learner Workload 0.00 Hours

Resources
Book Resources
Doran, P.M., Bioprocess Engineering Principles, Academic Press, 2006.
Other Resources
http://www.cheric.org/educational/control (Introduction to process control; understand the measurements - DP cell; Understand the actuator - control valve; PID controller tuning using various methods; Open loose response in the time and frequency domains; Closed loop PID response and stability; Feedforward and cascade control.)

http://www.pc-education.mcmaster.ca/instrumentation/go_inst.htm (Sensors, instrumentation and control valves).
Url Resources
Additional Info